Psoriasis Forum Malaysia
Would you like to react to this message? Create an account in a few clicks or log in to continue.

Novel methothrexate-based topical therapies for effective tr

Go down

Novel methothrexate-based topical therapies for effective tr Empty Novel methothrexate-based topical therapies for effective tr

Post by sindhu88 Thu Jul 15, 2010 8:35 pm

To reduce such effects, it would clearly be preferable to administer MTX topically [10]. In spite of several advantages offered by the transdermal route, few molecules can be administered topically/transdermally because of the formidable barrier properties of the stratum corneum (SC). A major problem in this case is the hydrosolubility of the drug and its relatively high molecular weight (454.56). Also the presence of the drug mostly in its dissociated form at physiological pH further limits its capacity for passive diffusion. Hence various techniques have been employed for enhancing the dermal delivery of MTX.

===========================

New Homes | Cheap Flights


sindhu88

Number of posts : 3
Registration date : 2010-07-14

Back to top Go down

Back to top


 
Permissions in this forum:
You cannot reply to topics in this forum